Hook Worm, Wiggle Worm etc. Stat options are: +1.0 Damage, +0.6 Tears, +0.2 Speed, +5.25 Range, Also drops either a bomb, a key or 3 coins on the ground. * , the lost item pool, head, bone, grey, gray, Gives Isaac a higher chance to find pills, Gives Isaac a higher chance to find Tarot cards after clearing a room or from chests, After clearing a room, you have a chance to heal for half a red heart, *, the lost item pool, silver, metal, grey, gray, isaacs fork, When taking damage, Isaac has a chance to deal damage to the entire room in a Necronomicon style effect, The chance to damage enemies is affected by your luck stat and at +50 or more Luck it will activate 50% of the time, * , the lost item pool, pink, purple, paper, red, Everytime you pick up a penny, you have a 25% chance to spawn a red heart on the floor, UNLOCK: Unlock this item by beating the Chest with Samson, * , the lost item pool, red, coin, cent, money, Everytime you pick up a coin, you have a 25% chance to spawn a bomb on the floor, UNLOCK: Unlock this item by beating Challenge #13 (Beans! After taking two hits, the fire will be extinguished, The Book can be held at the same time as another active item. You can pick which dice you want to use. Holding the fire button charges a spin attack (Damage * 8 + 10). He won't respawn even if you move to a new floor, Will always match your current movement speed, UNLOCK: Unlock this item by defeating The Beast as Tainted Keeper, Only found in the Mausoleum/Gehenna II boss room, The item itself has no effect, but triggers the ascent through the backwards path towards the Home floor. It's possible to hold more than one trinket by taking Mom's Purse, Belly Button or using the Smelter to convert them into passive items. A slow pulsing outline HUD effect appears for cards that would be buffed by Tarot Cloth, To see the full list of Tarot Card effects, check out the Mechanics > Tarot Cloth page, Every time you take damage, 10 high damage tears are fired in a circle around you (similar to the Tammy's Head effect), Tear damage is equal to Isaac's tear damage + 25 flat damage, Additionally, has a chance to activate the Anemic effect when taking damage for 2 seconds, Similar to Tammy's Head, this item synergizes with a lot of items (i.e. The main purpose of the Cracked Key is to unlock Tainted character in the Home floor without needing to find the Red Key. ?, Keeper and The Forgotten, UNLOCK: Unlock this item by defeating The Beast as Samson, The first time you take damage in a room, Isaac will become a ghost and time will stop for 3 seconds, During this ghost effect, you gain flight, spectral tears and the damage from the next hit you take is negated, Isaac returns to his body if you either clear the room or take damage while in ghost form, Only happens once per room - taking damage a second time does not turn you into a ghost again, UNLOCK: Unlock this item by defeating The Beast as Lazarus, Your tears are replaced with a charge attack that fires a homing, spectral fetus, The fetus tears deal damage equal to 75% of your current tear damage while in contact with enemies, roughly 5 times per second, Can't be held down like normal charge attacks, they will release automatically at full charge, UNLOCK: Unlock this item by defeating The Beast as Lilith, Gives you a familiar that can be charged up to release a black ring, that damages any enemies that touch it with rapid hits (similar to Maw of the Void / Athame effects), The effect does a decent amount of damage, but doesn't scale with your damage upgrades, UNLOCK: Unlock this item by defeating The Beast as Azazel, While firing tears, you now charge up a poop attack for 3 seconds that when released, fires from Isaac's behind, The poop attack deals your current tear damage to any enemies caught in the blast, Counts as 1 of 3 poop items needed towards the Oh Crap transformation. with Brimstone it fires 10 lasers), Turns your tears into bones, which shatter into 1-3 smaller bone shards upon hitting any object or enemy, The smaller bone shards deal damage equal to half your normal tear damage, UNLOCK: Unlock this item by defeating Delirium in The Void floor with Lazarus, Allows Isaac to carry two cards, runes or pills (or any combination of these) at the same time, Drops a random card, pill or rune on pickup, UNLOCK: Unlock this item by beating Greedier Mode with The Lost, Item Pool: Boss Room, Beggar, Gold/Stone Chest, *, silver, metal, grey, gray, omega, dads lost coin, dad lost coin, dad coin, REPENTANCE - This was renamed from Moldy Bread, *, sandwich, toast, brown, green, bite, bitten, Each time you take damage from any source, Cone Head has a 20% chance to prevent it from reducing your health, Isaac flashes blue very briefly when damage is negated by this item, * northernlion, nl, northern lion, ryan letourneau, egg, egg father, egg daddy, dad, BALD, northernlion's head resembles an egg much like this item, isn't that hilarious?, pink, Isaac's tears have a 20% chance to be a booger instead, which stick on to enemies and deal periodic poison damage until they die, Each tick of poison damage is equal to your normal tear damage, Each booger persists for 10 seconds or until the enemy dies. Explosions now only heal Isaac for half of a heart (previously healed a full heart), * item room, treasure room, item room pool, fire, heart, orange, burning, stannis, Makes tears break into 4 smaller tears on impact with anything, which deal half of your damage, * item room, treasure room, item room pool, brown, orange, headless, crickets body, When getting hit, this item has a chance to drop a soul heart or black heart, The chance to spawn a heart is affected by your luck stat and at +22 Luck it will activate 50% of the time, Enemies have a chance to drop half a red heart when killed, Item Pool: Item Room, Devil Room, Curse Room, Demon Beggar, * curse room pool, demon beggar pool, demon judgement pool, devil beggar pool devil pool, devil room pool, devil deal, item room, treasure room, item room pool, gimp mask, the lost item pool, grey, gray, black, An item only found in the secret room pool, * secret room pool, , the lost item pool, purple, black, grey, gray, flower, mtg magic the gathering, vintage, When you take damage, 1-2 coins will drop on the floor, When playing as the Keeper, this item drops 0-1 coins instead, * shop room pool, shop item pool, item room, treasure room, item room pool, pink, oink, Isaac's tears have a 15% chance of causing a fear effect, Feared enemies will run away from Isaac temporarily, The chance to fear enemies is affected by your luck stat and at +85 Luck it will activate every time, * dungeon room, blood challenge room, arena pool, item room, treasure room, item room pool, (D20 effect), 3 Dot - Rerolls all pickups on the entire floor, 4 Dot - Rerolls all pedestal items on the floor. First, you must defeat Mother. Doesn't include Curse Room doors or spiked rocks, Tears can be controlled mid-flight using the directional keys, In addition to regular tears, Isaac will sometimes fire extra spectral tears that orbit around him, Fully heals all your red heart containers, Isaac now emits a large light aura that damages nearby enemies 5 times per second while touching it, The visual effect is similar to the effect given to tears by the GodHead item, The aura deals more damage towards the center, ranging from 0.75 at max range to 4 damage when touching Isaac, In addition to normal tears, Isaac now also fires a set of 4 quadshot tears with a slowing effect, The quadshot tears deal 1.5 damage each and do not scale with your damage upgrades, Upon taking damage, you have a chance to dislodge the spider from your face. The door can only be opened if you have The Polaroid, The Negative or Faded Polaroid (the item/trinket is taken away when it opens). If you haven't unlocked Holy Mantle for The Lost yet, you won't gain the effect after touching a white fire so be careful! character damage multipliers), This item can only reduce your heart containers and will not increase them if you change back into a character with more health. Mini-bosses and bosses create 2-3 souls, When activated, the urn can be fired as a high damage flamethrower in any direction, A charge is consumed roughly every 0.5 seconds of use, Multi-part enemies such as Envy or Teratoma create a soul per each part killed, A maximum of 20 souls can be held in the urn at one time, UNLOCK: Unlock this item by beating Satan as Bethany, With each shot fired, another bloody tear will spawn behind Isaac, Spawning multiple tears will form a trail of tears that follow Isaac as he moves, bursting and dealing damage upon contact with enemies, The effect from this item will only work while in a hostile room that contains at least 1 enemy, UNLOCK: Unlock this item by defeating Mother in the Corpse II as Judas, Upon use, this item consumes 1 heart container or 2 soul hearts and spawns one item pedestal from the current room's pool, Every use gives a broken heart, meaning that slot is permanently broken and the maximum health limit is reduced by 1 for the rest of the run, If Isaac has 12 broken hearts, he dies instantly (this also applies to The Lost despite having no health), Magic Skin will continue to appear after finding it once if you are not still holding it - the chance for it to replace an item is 1 (12 - number of times used) up to a maximum of 50%, Broken hearts are empty heart containers that cannot be removed or refilled and will override other types of hearts when you reach 12 total. As you slide more elements, the others will be eliminated and the others will be rolled softly There are lots of things to unlock, with many of them connected to defeating certain bosses. UNLOCK: Unlock this card by defeating Ultra Greedier mode as Tainted Bethany, Spawns a random pedestal item from the current room's item pool, In exchange, turns one heart container or 2 soul hearts into a broken heart. This is intended give you a guaranteed way to teleport out of the Mom's Foot fight, for accessing the path to the Mausoleum floor. Unfortunately, some of these unlocks are obtainable while beating Mother and currently on PS4, it does happen that the game will crash while entering the fight. pills for Marbles. Isaac's head will remain stationary and fire tears. binding of isaac: repentance unlock guide. Recharge time: Starts at 1 second, increasing by every time you use it. However, If you also have flying you will always take damage, * astrology, astronomy, item room, treasure room, item room pool, blue, glow, circle, bomb, A random chance when you take damage to get an invincibility shield for 7 seconds, The chance to get an invincibility shield is affected by your luck stat and at +10 Luck it will activate every time you get hit, Converts all negative pills into their positive counterparts e.g. with Lilith, After picking up 15 hearts, Isaac gains a permanent angelic familiar and a soul heart drops, Possible familiars include: Holy Water, Guardian Angel, Sworn Protector, The Relic and Seraphim, It is possible to get multiple followers by continuing to pick up hearts, at intervals of 15 hearts each, After all 5 familiars have spawned, it will just drop a soul heart every 15 hearts collected, UNLOCK: Unlock this item by beating Boss Rush with Lilith, Two items now spawn in each of your item rooms, however only one can be taken and the other will disappear, A crown that replaces normal tears with blue diamond tears while you don't have any empty red heart containers or bone hearts, While the effect is active, tears do double damage and have -0.30 Shot Speed, The crown will glow blue while active, if inactive it will appear grey, The effect will also deactivate for the rest of the current room when you take damage, regardless of your health, When a room clear would otherwise yield no rewards, it now spawns 1-3 pennies, REPENTANCE - Deep Pockets no longer adds a pill/card slot, instead increases money cap to 999, UNLOCK: Unlock this item by beating The Chest floor with Keeper, A flying familiar that bounces around the room with a damaging aura, dealing rapid damage to any enemies inside it and boosting Isaac's tear damage, While standing in the black aura, Isaac has a temporary 1.5x damage multiplier (this will stack if you have more than one Succubus), The aura deals 2.5 damage per tick or about 7.5 - 10 damage per second, UNLOCK: Unlock this item by beating The Lamb with Lilith, Gives you a different tear effect with every tear that you fire, Tear effects include: Anti-Gravity, Ball of Bandages (Lvl 4), Bumbo (Lvl 3), Continuum, Cupid's Arrow, Compound Fracture, Euthanasia, Explosivo, Eye of Greed, Fire Mind, Flat Stone, Flat Worm, God's Flesh, Godhead, Head of the Keeper, Holy Light, Hook Worm, Ipecac, Iron Bar, Jacob's Ladder, Knockout Drops, Lachryphagy, Little Horn, Lodestone, Mom's Contacts, Mom's Eyeshadow, Mom's Perfume, Mucormycosis, My Reflection, Mysterious Liquid, Ocular Rift, Ouija Board, Ouroboros Worm, The Parasite, Parasitoid, Polyphemus, Pop!, Proptosis, Pulse Worm, Ring Worm, Rotten Tomato, Rubber Cement, Serpent's Kiss, Sinus Infection, Spider Bite, Strange Attractor, Sulfuric Acid, Technology Zero, Tiny Planet, Trisagion and Wiggle Worm, With Dr. Fetus, this item will also cycle through random Bomb Modifiers (e.g. No coding knowledge needed! * shop room pool, shop item pool, the lost item pool, white, Causes Isaac's head to detach and orbit his body, blocking shots and dealing 7 contact damage per tick, BFFs will cause the Guillotine head to do double damage (14 damage per tick), Tears are still fired from Isaac's head but the hitbox remains around his body, UNLOCK: Unlock this item by beating the Isaac boss with Judas, * item room, treasure room, item room pool, chop, head, silver, metal, Gives Isaac an orbital ball of bandages that deals 7 contact damage per tick and blocks enemy shots, Collecting a second Ball of Bandages in the run turns the orbital into a pink head that shoots tears that deal 7 damage each and have a chance to charm enemies, Getting a third Ball of Bandages will transform the head into bandage girl which will chase enemies dealing 3.5 contact damage per tick while firing charm tears, A fourth Ball of Bandages will make the Bandage Girl bigger and stronger, making her deal 5.5 damage per tick instead, Any further Ball of Bandages will repeat the cycle, Increases the chance of champion enemies appearing by 15%, Doesn't affect the chance for champion bosses to spawn, * shop room pool, shop item pool, red, croissant, crescent, Bombs now become poop bombs, which deal 10 damage to all enemies in the room and daze them for a short period of time, Butt Bombs heal the poop bosses (Dingle, Dangle, Brownie) by 25% of their max HP, * boss rush pool, boss rush room, item room, treasure room, item room pool, poop, face, brown, If Isaac stands still and stops shooting for a second, he turns to stone, making him invincible until he moves/shoots again, Using bombs or your active item will remove the invicibility as well, This item is a reference to the Tanuki suit in Super Mario 3, * item room, treasure room, item room pool, raccoon, green, Spawns 2-5 friendly attack spiders every time you take damage, REPENTANCE - Buffed, used to spawn 1-2 spiders, * item room, treasure room, item room pool, the lost item pool, purple, blue, heart, cute spider baby, When Isaac dies, he has a 50% chance to resurrect with 1/2 a heart, * curse room pool, red chest pool, red chest item pool, devil pool, devil room pool, devil deal, Happens a total of 3 times over 30 seconds, ??? Eden I find very fun as well due to his randomness. 11 Death Certificate. Gives Isaac a little portal familiar, that moves across the screen as you're firing, The portal will suck up any consumables and trinkets it travels over, causing it to become larger and deal more contact damage, When the portal sucks up 4 pickups, it turns into a portal that can be used to teleport to unexplored rooms around the floor. Demo man unlocks a card that can instantly kill any enemy, including end bosses. 8 Spelunker Hat. On Bethany and J+E, i didn't encountered this glitch. Having a higher movement speed allows you to kick it harder, Enemies hit by the cube while moving have a high chance to become frozen. Blue Baby, The Lost), * devil pool, devil room pool, devil deal, red, black, star, moon, When used, gives a random familiar for the entire floor. - Gives the curse of the maze effect for the current floor. Counts as 1 of 3 familiar items needed towards the Conjoined transformation. Stick to Normal Mode The Binding of Isaac: Repentance has two main difficulty settings for the game's primary mode. UNLOCK: Unlock this trinket by defeating Mother as Tainted Lost, Has a decent chance for Devil Deals to cost money instead of Health, The conversion rate is 1 heart container to 15 coins, Items can be on discount similar to the shop, making it 1 heart container = 7 coins instead, Can be dropped to disable this effect while in the room, UNLOCK: Unlock this trinket by defeating Isaac, ?? With the nerf to the Devil Room pool quality overall, this item is the strongest new addition to that pool. Cube of Meat after defeating a Horseman, REPENTANCE - It is now possible to see items again that have been rerolled away, preventing emptying the item pool and 'Breakfasting', REPENTANCE - Chaos now assigns a "weight" to item pools based on how many items are in the pool. ?, Satan and The Lamb as Tainted Lazarus, All new chests become locked Golden chests, UNLOCK: Unlock this trinket by defeating Isaac, ?? After a few seconds a huge missile hits the target and deals 20x your tear damage to anything nearby, Essentially a one-time use of the Epic Fetus item, * item room, treasure room, item room pool, grey, gray, robot, Isaac's tears now have a piercing effect which allows them to travel through enemies instead of breaking on hit, * item room, treasure room, item room pool, arrow, penetrative, penetrating shots, grey, gray, Carry them with you", "The walls will harden over time. How do you unlock Godhead? While so simple in theory, Psy Fly is undoubtedly a top-tier item that players were shocked to learn is unlocked from the very start of the game. Amnesia becomes I Can See Forever etc, Adds 0-2 coins to the payout when you use a Blood Donation machine or IV Bag, * shop room pool, shop item pool, item room, treasure room, item room pool, pink, yellow, paper, Reveals the entrance to secret rooms and automatically opens the hole, removing the need for bombs to enter, * item room, treasure room, item room pool, xray vision, xray glasses, pink, white, black, Gives Isaac invincibility and +0.28 Speed for 6 seconds, While active you cannot fire tears, but running into enemies will deal 40 contact damage per second, Allows free hits on the Blood Donation machines and devil beggars, * item room, treasure room, item room pool, white, horn, Upon use, gives Isaac an extra Soul heart, Using this item gives you a higher chance of finding a horsemen boss at the end of the floor, +17.5% chance of a Devil Deal opening after the boss fight, UNLOCK: Unlock this item by beating one of the horsemen bosses for the first time, Item Pool: Item Room, Library, Angel Room, * library pool, library room, book room pool, item room, treasure room, item room pool, The effect is shown visually in 3 stages with the character's belly getting larger each time until it finally gives birth to a familiar. ?, Satan and The Lamb as Tainted Eve, A small clot friend will hug Isaac, following his exact movements (similar to how Jacob & Esau work) and shooting tears when he does, The clot can be moved around by collision with an object/wall, allowing you to re-position it, The clot's damage is roughly 1/3 of your tear damage, If it takes a few hits it will die, and respawn in the next room, UNLOCK: Unlock this trinket by defeating Mother as Tainted Eve, Spawns a random chest after completing a regular Challenge Room, Spawns a pedestal item after completing a boss Challenge Room, UNLOCK: Unlock this trinket by defeating Isaac, ?? What's new in Isaac repentance? Unlock Condition: Repentance added many new items into the Secret Room that basically instantly win you the run such as the Red Key, Rock Bottom ( ), and Echo Chamber ( ). No, i don't think so. e.g. #9 Black May 23, 2021 @ 11:46am Originally posted by Squaredudes: Enemies include Candler, Lil' Haunt, Polty, Red Ghost, Wizoob and The Forsaken, The Haunt, The Heretic and The Rainmaker bosses. REPENTANCE - White Pony's charge time has been reduced to 2 (from 6). Guide to Unlock Marbles Step 1: Unlock Tainted Cain (Spoilers) If you haven't yet, you'll need to unlock Tainted Cain. achievement (complete a victory lap, defeating the lamb boss), Horf! The only way to remove broken hearts is by donating to a Confessional Machine, UNLOCK: Unlock this item by defeating Mother in the Corpse II as Jacob & Esau, Holding the fire button charges up a light beam attack similar to Brimstone, The light beam deals damage equal to your current tear damage per tick to any enemies touching it, UNLOCK: Unlock this item by defeating Mother in the Corpse II as Bethany, When picked up, this item gives you a stat increase, based on which is currently the lowest. Here i will tell you how to unlock all of the new reverse tarot cards, that came with the release of the new DLC repentance. UNLOCK: Unlock this item by defeating The Beast as ??? For everything it increases by 1 coin * the number of purchases, The max price of an item is always 99c with this item, Works with Keeper's Box and the Member Card extra shop, Most spider enemies no longer target or deal contact damage to Isaac, This is very similar to a Skatole for spiders instead of flies, Continuously firing or charging tears for 3 seconds causes Isaac to fart and drop a Butt Bomb, Only 1 Butt Bomb can be dropped per charge, so you'll need to stop firing then start again to drop another one, Butt Bombs explode for 50 damage like normal bombs, but also deal 10 damage to all enemies in the room and daze them for a short period of time, *, yfront, y-front, underpants, underwear, white, grey, gray, no 2, number two, number 2, no two, Transforms Isaac's tears into a wide arc shape which doubles their size and hitbox, *, flat, white, grey, gray, blue, drip, water, eyes, This item turns all doors that require a key into doors which need a coin to enter instead, This affects shops, item rooms, libraries, double locked doors, key blocks, chests and other key doors, Changes the appearance of doors and objects that this item works on to show a coin slot instead of a keyhole, Item Pool: Shop, Greed Mode Item Room, Greed Mode Shop, *, grey, gray, metal, slot, rectangle, silver, Gives you a random item at the start of your next run (You need to start a fresh run to receive the item), Important progression items such as Key Pieces or the Mom's Shovel pieces cannot be given by Eden's Blessing, UNLOCK: Unlock this item by beating Blue Womb (Hush) with Eden, When used, can be thrown at enemies to capture them (similar to a Pok Ball), After capturing an enemy, the next use of the Friendly Ball will re-spawn the same enemy as a friendly companion which will attack other enemies, The companion will persist between rooms and floors until it dies by taking enough damage, Walking over the thrown ball after capturing an enemy will immediately recharge it, *, pokemon, grey, gray, blue, deathstar, circle, When used, will detonate any tears currently on the screen and cause each one to split into 6 more tears which will fire in a circle, similar to Tammy's Head, Luck-based items such as Holy Light are applied to each tear individually, Gives Isaac a familiar Gurdy that will charge around the room dealing contact damage to enemies, The Gurdy is charged by holding down the fire button and letting go. 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